Madecassoside
Key Centella asiatica saponin used for soothing and repair claims; evidence moderate for barrier/redness endpoints.
Madecassoside is a pentacyclic triterpene glycoside from centella asiatica. It is one of the standardised Centella markers (with asiaticoside, madecassic and asiatic acids) used in repair balms such as panthenol-centric formulas[1][2].
What it does
Preclinical and clinical Centella work supports wound-healing, collagen-support, and anti-inflammatory directions; madecassoside is frequently the labelled active fraction in leave-ons[1].
The evidence
Human data are stronger for Centella extracts/fractions in wound and scar contexts than for every cosmetic redness claim; grade sits at moderate overall[1][2].
How to use it
Look for it beside panthenol in repair balms. Patch-test if you react to botanical actives generally.
Evidence by claim
Safety & limits
Sources · 2
- [1]Bylka W, Znajdek-Awiżeń P, Studzińska-Sroka E, et al.. Centella asiatica in cosmetology. Postępy Dermatologii i Alergologii (2013)doi:10.5114/pdia.2013.33378
- [2]Gohil KJ, Patel JA, Gajjar AK. Pharmacological properties of Centella asiatica and its therapeutic potential. Indian Journal of Pharmaceutical Sciences (2010)doi:10.4103/0250-474X.78519