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Wednesday, October 14, 2026Index last updated Oct 14
The Index  ·  Centella triterpene aglycone

Madecassic Acid

Madecassic Acid

Centella asiatica triterpene aglycone paired with madecassoside in marker HPLC panels for extract characterisation.

EmergingIn-vitro or early data only
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Written byTheSkindex Desk
Reviewed byNot yet reviewed
Last updated5 Oct 2026
Sources2 cited

Madecassic acid is commonly included with madecassoside, asiaticoside, and asiatic acid in Centella marker panels[1].

What it does

Composition and identity marker in extract analytics rather than a freestanding retail grade ladder[1].

The evidence

Refer to CIR Centella-derived ingredient assessments for reviewed ingredient families.

How to use it

Read beside madecassoside and centella asiatica when labels or specs mention the acid marker.

Evidence by claim

Graded separately; the entry grade is the best-supported claim
Centella asiatica triterpene aglycone paired with madecassoside in marker HPLC panels for extract characterisation.[1]
Emerging

Safety & limits

Source and region, always
all — Draft Index entry only. No invented regional limit or Hotlist status; consult cited CIR/SCCS/regulator sources before any safety claim.[1] CA US EU UK

Sources · 2

Numbered as cited in the text
  1. [1]Cosmetic Ingredient Review. Cosmetic Ingredient Review (CIR) programme materials. CIR (2015)regulator
  2. [2]NCBI PubChem. PubChem compound record (identity reference). PubChem (2024)other

Revision history

18 Sept 2026Drafted by botTheSkindex Desk
Madecassic Acid — evidence, limits and safety · theskindex