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Tuesday, October 13, 2026Index last updated Oct 9
The Index  ·  Acylphosphine oxide photoinitiator

Bis-Trimethylbenzoyl Phenylphosphine Oxide

Bis-Trimethylbenzoyl Phenylphosphine Oxide

Light-stabilizer photoinitiator grouped with TPO in the September 2026 CIR Draft Tentative Report; safety conclusion still open.

EmergingGrouped in CIR Draft Tentative Report with outstanding IDA items.
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Written byTheSkindex Desk
Reviewed byNot yet reviewed
Last updated18 Sept 2026
Sources1 cited

Bis-Trimethylbenzoyl Phenylphosphine Oxide is reported to function as a light stabilizer. CIR added it to the trimethylbenzoyl Diphenylphosphine Oxide review after a 2025 read-across decision and is advancing a Draft Tentative Report for the October 2026 meeting.[1]

What it does

As a photoinitiator / light stabilizer it is meant to manage light-driven chemistry in finished formulas, overlapping the nail-focused TPO file rather than acting as a classic skincare active.[1]

The evidence

Staff note outstanding requests for sensitisation at maximum use, phototoxicity outside nail products, non-nail use concentrations, impurities, and method of manufacturing for this ingredient and Ethyl Trimethylbenzoyl Phenylphosphinate.[1] Grade stays emerging until the Panel closes those gaps or issues a qualified conclusion.

How to use it

Check the INCI list on nail and specialty formulas; do not treat marketing copy as a substitute for the pending CIR conclusion.

Evidence by claim

Graded separately; the entry grade is the best-supported claim
Reported light stabilizer in cosmetics; CIR review ongoing[1]
Emerging

Safety & limits

Source and region, always
all — No CIR final conclusion as of September 2026 Draft Tentative Report.[1] US

Sources · 1

Numbered as cited in the text
  1. [1]Draft Tentative Report: Safety Assessment of Bis-Trimethylbenzoyl Phenylphosphine Oxide, Ethyl Trimethylbenzoyl Phenylphosphinate, and Trimethylbenzoyl Diphenylphosphine Oxide. Cosmetic Ingredient Review (2026)

Revision history

18 Sept 2026Drafted by botTheSkindex Desk