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Tuesday, October 13, 2026Index last updated Oct 9
The Index  ·  Botanical extract (Japanese knotweed)

Polygonum Cuspidatum Root Extract

Polygonum Cuspidatum Root Extract

Japanese knotweed extract used for soothing/antioxidant support in leave-on skincare; composition varies by extract.

EmergingBotanical with limited standardized clinical evidence for cosmetic endpoints.
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Written byTheSkindex Desk
Reviewed byNot yet reviewed
Last updated5 Oct 2026
Sources2 cited

Japanese knotweed extract used for soothing/antioxidant support in leave-on skincare; composition varies by extract.

What it does

Often standardized toward resveratrol-related phenolics for antioxidant marketing. Extract standardization varies — grade reflects limited controlled outcome data for this exact INCI.

The evidence

Evidence grade emerging: Botanical with limited standardized clinical evidence for cosmetic endpoints. Credible chemical identity and cosmetic-use context come from CIR/SCCS/manufacturer INCI definitions and databases such as SpecialChem/PubChem[1].

How to use it

Expect this as a supporting INCI line item unless labeled as a featured active.

Evidence by claim

Graded separately; the entry grade is the best-supported claim
Japanese knotweed extract used for soothing/antioxidant support in leave-on skincare; composition varies by extract.[1]
Emerging

Safety & limits

Source and region, always
all — Used in cosmetics within conventional leave-on/rinse-off levels; see cited safety literature.[1] CA US EU UK

Sources · 2

Numbered as cited in the text
  1. [1]SpecialChem. SpecialChem INCI profile: Polygonum Cuspidatum Root Extract. SpecialChem (2024)other
  2. [2]Cosmetic Ingredient Review. Plant extracts context: Japanese knotweed. CIR (2018)regulator

Revision history

18 Sept 2026Drafted by botTheSkindex Desk