Ethyl Tafluprostamide

Ethyl Tafluprostamide is a synthetic prostaglandin analogue listed as a hair- and nail-conditioning agent. It is under joint CIR review with isopropyl CloprostenateIsopropyl CloprostenateEmergingIsopropyl Cloprostenate · Synthetic prostaglandin analogueProstaglandin analogue in some lash serums; EU SCCS said it is not safe for eyelash/eyebrow growth cosmetics, while a US Panel draft tentative report is still open.Open in the Index →.[1]

What it does

Prostaglandin analogues are used in some eyelash and eyebrow growth cosmetics because related drug-class molecules can lengthen the hair cycle. That pharmacology is exactly why regulators scrutinise ocular side effects (intraocular pressure, iris colour change, periorbital fat loss).[1][2]

The evidence

CIR released a revised Draft Tentative Report on 11 September 2026 after earlier insufficient-data announcements and a 2024 table to wait for industry studies.[1] Separately, the EU Scientific Committee on Consumer Safety concluded in February 2026 that three prostaglandin analogues assessed for lash and brow growth — including isopropyl cloprostenate — could not be considered safe for that use, citing potent pharmacology and inadequate data to exclude adverse effects.[2] Ethyl tafluprostamide itself was not one of the three SCCS-named molecules, but it sits in the same analogue class CIR is weighing.

How to use it

If a lash serum lists this INCI, treat it as a pharmacologically active analogue, not a bland conditioner. Prefer products and markets that disclose concentration and ocular-risk labelling; watch the October CIR meeting for a US Panel conclusion.